Two packs of werewolves, divided by principles, are signaled by the moon of the coming of an ancient prophecy. A boy named Timothy approaches his 13th birthday, unaware this marks the time of his transformation. He has been raised by his grandmother Nana, his mother Rachel, his uncle Jonas, his cousin Katherine and Katherine's boyfriend, Adam. His father is said to be dead. Rachel and Timothy have been unaware that the rest of the family are "good" werewolves who have guarded Timothy and his secret since birth. They know that he is a "half-blood" who is prophesied to end the curse. But they also know that his power will put him in danger, for other werewolves embrace their blood-lust and are bent on killing the boy. Four of these werewolves are a motorcycle pack—leader Varek, and cohorts Zo, Sonya, and Grenier, who use a hawk as an airborne spy—who track down Timothy in the small town of Huguenot. Varek discovers the location of Timothy. Reaching Huguenot, he sees Nana and Timothy and proceeds with a gunfight between his pack against the "good" werewolves and various townspeople. Adam's father is killed, and Nana sacrifices herself to let Timothy and the others escape. Jonas explains the situation to Rachel and Timothy, and they are convinced after Jonas and others turn into werewolves at night. The next day, Timothy faints and is sent to a hospital. Varek's gang infiltrate the hospital and attack Timothy. Grenier is killed by Adam while Katherine is being held hostage by Varek. It is revealed that Varek was Caleb, Rachel's husband and Timothy's father, who was abducted and forcibly turned into Varek during an attack when Timothy was a baby. After escaping, Adam finds Katherine and brings her back. At sundown, Katherine was discovered to have been forced to feed on humans and kills Adam with his own gun. Just as Katherine is about to attack Timothy, Jonas kills her with a gunshot in the back. They find their next safe place, with Rachel and Timothy hiding in a steel cage while Jonas sets out to ambush Varek, Zo, and Sonya. Zo is killed after being trapped and dropped from a height. Sonya tries to attack Rachel and Timothy but is shot by Timothy. Rachel then finishes Sonya off. Varek tries to kill Timothy but is stopped by Jonas. They struggle, and Jonas feeds on Varek's arm and knocks him unconscious. Taken over by the blood frenzy, Jonas attempts to attack Timothy but is shot to death by Rachel. Varek wakes up and bites Timothy, but the clock chimes midnight. He is struck by Rachel and knocked to the ground. As Rachel and Timothy approach him, they witness him transform back into Caleb, revealing that Timothy's blood is the cure. Timothy and Rachel rush to Caleb's side and share an emotional reunion. Later they are shown traveling around administering the cure to those who want it while using bullets filled with Timothy's blood on those who attack them. The film leaves off with Timothy saying, "For some I am salvation, for the others their destruction.”
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